Why a Bioresorbable Scaffold ?

The role of a coronary stent implanted during PCI procedure is to provide temporary scaffolding to the blockage or lesion site, as well as to deliver a drug to facilitate healing. Once the lesion has healed, there is no need for the stent to remain inside the body. To offer an analogy, just as paracetamol is not required once a headache passes, or a plaster support is not required once fractured bones heal.

Currently, metallic drug eluting stents remain in the body as a permanent implant. This may not only lead to increased risk of adverse events year on year, but may also pose a hindrance if future procedures need to be performed in the same artery.

BRS provides a temporary scaffold to the lesion to restore the blood flow, once the vessel blockage is treated and healing is completed, BRS dissolves fully, leaving the artery in its natural state with no foreign residue. This provides both physicians and patients the room to explore future treatment interventions, if required, in the same blood vessel.

Evolution of PCI

The field of interventional cardiology has evolved significantly since the first percutaneous coronary angioplasty was performed 40 years ago. This evolution began with a balloon catheter and has progressed into bare-metal stents (BMS), Drug-eluting stents (DES) and culminates with the advent of Bioresorbable stents.

Diagram shown below represents evolution of Percutaneous Coronary Intervention (PCI)

MeRes100™ - Next Gen BRS

MeRes100™ BRS next-generation bioresorbable technology with a low strut thickness of 100 microns which fully resorbs naturally in the artery within 2-3 years, thus restoring the vessel to its true form and nature. The design of MeRes100™ scaffold addresses the limitations of the previous generation scaffold and in a true sense is the next revolution in bioresorbable technology

Phases of Healing with BRS*

Post Scaffold placement body undergoes healing in the following manner